By Dr. Jeffrey Peng, MD · Published March 6, 2026 · 5 min read Watch the Full Video Dextrose prolotherapy is one of the oldest regenerative injection therapies still in use today, yet most patients have never heard of it. The concept is simple: inject a concentrated sugar solution into or around a damaged joint to trigger the body’s natural healing response. But does the science actually support this approach for knee arthritis ? In this post, we review the clinical trial ev

By Dr. Jeffrey Peng, MD · Published March 6, 2026 · 6 min read Watch the Full Video Both hyaluronic acid (HA) injections and platelet-rich plasma (PRP) injections are well-established treatments for knee osteoarthritis. When used individually, head-to-head trials consistently show that PRP tends to produce more favorable outcomes than HA alone. But a growing body of research is now exploring whether combining the two injections could produce a synergistic effect — offerin

By Dr. Jeffrey Peng, MD · Published March 6, 2026 · 12 min read Watch the Full Video Myofascial pain syndrome and trigger points are among the most common — and most commonly missed — causes of chronic musculoskeletal pain. In my sports medicine practice, I regularly evaluate patients who have seen multiple providers, undergone extensive imaging, completed months of physical therapy, and sometimes even had surgery — all without relief — because the underlying myofascial tri

By Dr. Jeffrey Peng, MD · Published March 6, 2026 · 7 min read Watch the Full Video Stem cell therapy continues to generate excitement as a potential treatment for chronic joint pain. Among the various sources of stem cells being studied, umbilical cord-derived mesenchymal stem cells have emerged as a particularly interesting option. Unlike bone marrow or adipose-derived stem cells — which are harvested from the patient's own body — umbilical cord stem cells come from donate

By Dr. Jeffrey Peng, MD · Published March 6, 2026 · 8 min read Watch the Full Video Platelet-rich plasma ( PRP ) injections have become a widely studied treatment option for tendon conditions such as tennis elbow, fascial problems such as plantar fasciitis, and joint conditions such as osteoarthritis. PRP is increasingly used as a first-line therapy because it is both safe and effective. However, one often-overlooked factor that can significantly influence your outcomes is t

Dr. Jeffrey Peng, MD · Published March 6, 2025 · 5 min read Watch the Full Video Amniotic fluid injections have generated significant interest as a potential treatment for knee osteoarthritis. One of the most compelling use cases is for patients who continue to experience pain despite standard treatments such as hyaluronic acid and corticosteroid injections. But does this treatment actually work? A recent clinical trial offers some encouraging — though nuanced — answers. Wh

By Dr. Jeffrey Peng, MD · Published March 6, 2026 · 6 min read Watch the Full Video Platelet rich plasma injections and stem cell injections are two of the most talked-about orthobiologic treatments for knee osteoarthritis. Both have demonstrated clinically significant pain relief and functional improvement in clinical trials. However, stem cell therapy is often marketed as a superior treatment and comes with a much higher price tag. But does the evidence actually support th

By Dr. Jeffrey Peng, MD · Published March 6, 2025 · 7 min read Watch the Full Video If you have been diagnosed with a degenerative meniscus tear, you have likely heard conflicting advice about treatment. Some physicians recommend arthroscopic surgery to remove the damaged tissue, while others advocate for physical therapy and structured exercise. The disagreement often depends on whether you see an orthopedic surgeon or a nonoperative sports medicine specialist. So which app

By Dr. Jeffrey Peng, MD · Published March 6, 2025 · 5 min read Watch the Full Video Hyaluronic acid injections and PRP therapy are two of the most effective non-surgical treatments for hip osteoarthritis. Both have been shown to reduce pain and improve function — but is one better than the other? And if both work, does combining them into a single injection produce even better results? A recently published randomized clinical trial directly compared PRP alone, hyaluronic ac

By Dr. Jeffrey Peng, MD · Published March 6, 2025 · 8 min read Watch the Full Video If you are considering a platelet rich plasma injection , one of the most important questions you can ask your provider is: how many platelets will be in my PRP? Research increasingly shows that platelet count is one of the strongest predictors of treatment success — and not all PRP preparations deliver an adequate dose. A growing body of evidence suggests that achieving at least 5 to 10 bill

By Dr. Jeffrey Peng, MD · Published March 6, 2025 · 5 min read Watch the Full Video There is considerable debate within the orthopedic community about the best treatment options for a meniscus tear. What is becoming increasingly clear is that cutting out the meniscus should be seen as a last resort. Newer techniques for meniscus repair surgery have shown lower failure rates, and with advances in orthobiologics and cellular therapy, many providers are exploring whether augme

By Dr. Jeffrey Peng, MD · Published March 6, 2026 · 6 min read Watch the Full Video If you are dealing with knee osteoarthritis and have been told that arthroscopic surgery might help, you may be wondering how it compares to platelet-rich plasma (PRP) injections. Head-to-head trials comparing PRP to placebo, hyaluronic acid, and cortisone injections have consistently shown that PRP produces superior and more sustained symptom relief. But how does PRP stack up against surger

By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 7 min read Watch the Full Video Platelet-rich plasma (PRP) injections have become one of the most effective non-surgical treatments for reducing pain and improving function in patients with knee osteoarthritis . But an important question remains: can PRP actually slow down the progression of arthritis itself? A landmark randomized controlled trial by Chu et al. (2022) set out to answer that question — and the results were

By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 8 min read Watch the Full Video Platelet rich plasma (PRP) and stem cell injections are among the most promising nonsurgical treatments available for joint pain and musculoskeletal conditions. However, because most insurance plans do not cover these procedures, cost is one of the most common questions patients ask before pursuing treatment. Understanding the typical price range, the factors that influence pricing, and — mos

By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 7 min read Watch the Full Video Muscle pain is one of the most overlooked contributors to knee osteoarthritis symptoms. When patients visit their doctor for knee pain, the evaluation typically focuses on the joint itself — the bones, cartilage, ligaments, and meniscus . But the muscles surrounding the knee are rarely examined, and research suggests they may be responsible for a substantial portion of the pain that patients

By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 8 min read Watch the Full Video If you have been diagnosed with knee osteoarthritis , one of the first questions you may ask is whether it is safe to keep walking. Many patients worry that physical activity will accelerate cartilage breakdown and make their condition worse. Some have even been told by well-meaning providers to stop exercising altogether. However, current evidence tells a very different story: walking is not

By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 6 min read Watch the Full Video If you have been told you have knee arthritis, your doctor likely used an X-ray to assess the severity of your condition. The most widely used classification tool for this purpose is the Kellgren-Lawrence (KL) grading system , which rates knee osteoarthritis on a scale from 0 to 4. A grade of 0 indicates no signs of osteoarthritis, while a grade of 4 represents severe, bone-on-bone arthritis

By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 5 min read Watch the Full Video Carpal tunnel syndrome is one of the most common causes of hand pain and numbness, affecting millions of people each year. Injections are frequently used to provide symptom relief, but which type of injection delivers the best results? A systematic review and network meta-analysis compared three injection options — platelet-rich plasma (PRP) , dextrose prolotherapy, and corticosteroids — to

By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 7 min read Watch the Full Video Glucosamine and chondroitin are among the most widely used dietary supplements for joint pain and arthritis. Walk into any pharmacy, and you will find shelves stocked with combination formulas promising relief. But despite decades of use, significant debate remains over whether these supplements actually deliver meaningful clinical benefits. A large 2018 systematic review published in the Br

By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 8 min read Watch the Full Video Turmeric and curcumin have been used in traditional Chinese medicine and Ayurvedic medicine for hundreds of years. Only recently has Western medicine begun to explore the surprisingly wide range of beneficial properties attributed to curcumin, including its ability to reduce pain and inflammation. But does the evidence support these claims? In this article, we review the results of several re