PRP works for knee arthritis — but only at the right dose. Blood draw volume and kit recovery rate determine whether your injection actually helps.

By Dr. Jeffrey Peng, MD · Published April 3, 2026 · 8 min read Watch the Full Video There is now MRI evidence that platelet-rich plasma (PRP) injections can help facilitate the regrowth of knee cartilage. A 42-year-old physically active male developed a progressive osteochondral defect after snowboarding. He tried rehabilitation, corticosteroid injections, and even standard PRP — none of which resolved his condition. His orthopedic surgeon recommended arthroscopic surgery.

By Dr. Jeffrey Peng, MD · Published March 6, 2026 · 6 min read Watch the Full Video Both hyaluronic acid (HA) injections and platelet-rich plasma (PRP) injections are well-established treatments for knee osteoarthritis. When used individually, head-to-head trials consistently show that PRP tends to produce more favorable outcomes than HA alone. But a growing body of research is now exploring whether combining the two injections could produce a synergistic effect — offerin

By Dr. Jeffrey Peng, MD · Published March 6, 2026 · 7 min read Watch the Full Video Stem cell therapy continues to generate excitement as a potential treatment for chronic joint pain. Among the various sources of stem cells being studied, umbilical cord-derived mesenchymal stem cells have emerged as a particularly interesting option. Unlike bone marrow or adipose-derived stem cells — which are harvested from the patient's own body — umbilical cord stem cells come from donate

Dr. Jeffrey Peng, MD · Published March 6, 2025 · 5 min read Watch the Full Video Amniotic fluid injections have generated significant interest as a potential treatment for knee osteoarthritis. One of the most compelling use cases is for patients who continue to experience pain despite standard treatments such as hyaluronic acid and corticosteroid injections. But does this treatment actually work? A recent clinical trial offers some encouraging — though nuanced — answers. Wh

By Dr. Jeffrey Peng, MD · Published March 6, 2026 · 6 min read Watch the Full Video Platelet rich plasma injections and stem cell injections are two of the most talked-about orthobiologic treatments for knee osteoarthritis. Both have demonstrated clinically significant pain relief and functional improvement in clinical trials. However, stem cell therapy is often marketed as a superior treatment and comes with a much higher price tag. But does the evidence actually support th

By Dr. Jeffrey Peng, MD · Published March 6, 2025 · 5 min read Watch the Full Video Hyaluronic acid injections and PRP therapy are two of the most effective non-surgical treatments for hip osteoarthritis. Both have been shown to reduce pain and improve function — but is one better than the other? And if both work, does combining them into a single injection produce even better results? A recently published randomized clinical trial directly compared PRP alone, hyaluronic ac

Research shows PRP only works above a certain platelet dose. Here’s the evidence on how many platelets you need — and what to ask your provider.

Average PRP cost is about $700 and stem cell about $2,700 — but price varies widely. Here’s what the data shows and why the provider matters more than the cost.

By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 7 min read Watch the Full Video Muscle pain is one of the most overlooked contributors to knee osteoarthritis symptoms. When patients visit their doctor for knee pain, the evaluation typically focuses on the joint itself — the bones, cartilage, ligaments, and meniscus . But the muscles surrounding the knee are rarely examined, and research suggests they may be responsible for a substantial portion of the pain that patients

By Dr. Jeffrey Peng, MD · Published March 5, 2025 · 7 min read Watch the Full Video Meniscus tears are one of the most common knee injuries, and for patients with degenerative tears, the standard recommendation from many orthopedic surgeons remains arthroscopic partial meniscectomy. However, a growing body of evidence suggests that surgery should be seen as a last resort for degenerative meniscus tears, not a first-line treatment. In fact, a comprehensive non-surgical treatm

Most insurance companies still refuse to cover PRP. Here’s why — and what the clinical evidence and major medical societies actually say.

By Dr. Jeffrey Peng, MD · Published March 5, 2025 · 7 min read Watch the Full Video If you have been diagnosed with knee osteoarthritis and are exploring injection options, two of the most common treatments you will encounter are platelet-rich plasma (PRP) and hyaluronic acid (HA) injections. Both are well-established, evidence-based treatments that can reduce pain and improve function, but they work through different mechanisms and come with different cost and insurance co

By Dr. Jeffrey Peng, MD · Published March 4, 2026 · 30 min read Watch the Full Video Platelet-rich plasma (PRP) injections have generated significant attention for their ability to treat joint pain, tendon injuries, and accelerate recovery using your body’s own healing mechanisms. But with growing interest comes a flood of questions: Does PRP actually work? How does it compare to cortisone or stem cells? Is the cost justified when insurance does not cover it? In this compreh

By Dr. Jeffrey Peng, MD · Published March 4, 2026 · 8 min read Watch the Full Video Cortisone injections have been a staple of musculoskeletal medicine for decades. They are fast, relatively inexpensive, and can deliver meaningful short-term pain relief for conditions ranging from arthritis to tendinitis and bursitis. But what does the clinical evidence actually say about the long-term consequences of cortisone shots on your tendons and joints? In my practice as a sports me

By Dr. Jeffrey Peng, MD · Published March 4, 2026 · 10 min read Watch the Full Video Living with knee osteoarthritis often means navigating a confusing landscape of treatment options, especially when it comes to injections. If cortisone shots have given you little to no lasting improvement, you are far from alone. The good news is that there are several alternatives worth considering, and the clinical evidence behind them continues to grow. In this guide, we will compare the

By Dr. Jeffrey Peng, MD · Published March 4, 2025 · 20 min read Watch the Full Video What Is Knee Osteoarthritis and Why Is It So Complex? Knee osteoarthritis is the most common form of arthritis and is defined by the progressive loss of cartilage within the joint. Despite its prevalence, most patients have a limited understanding of the condition and the full range of treatment options available. In my practice, I frequently encounter patients who have received incomplete o

By Dr. Jeffrey Peng, MD · Published March 4, 2026 · 12 min read Watch the Full Video Meniscus tears are among the most common knee injuries, affecting athletes and older adults alike. They can cause significant pain and disability in some people, yet in others they produce no symptoms at all. This disconnect is one of the main reasons there is so much confusion surrounding meniscus tear treatment — patients often receive conflicting advice from different providers. As a boar

Not all PRP is the same. Higher platelet doses consistently outperform low-dose preparations for knee arthritis — here’s the evidence.

Written by Dr. Jeffrey Peng, MD — Board-Certified Sports Medicine Physician Published: March 2, 2026 | Last Updated: March 2, 2026 If you are considering a PRP injection for knee arthritis, you may have come across the option to add hyaluronic acid (HA) to the treatment. It is a reasonable question: does combining PRP and hyaluronic acid actually produce better outcomes, or is it simply an expensive add-on with no meaningful benefit? The answer could influence your treatment