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Does Dextrose Prolotherapy Work for Knee Arthritis?
By Dr. Jeffrey Peng, MD · Published March 6, 2026 · 5 min read Watch the Full Video Dextrose prolotherapy is one of the oldest regenerative injection therapies still in use today, yet most patients have never heard of it. The concept is simple: inject a concentrated sugar solution into or around a damaged joint to trigger the body’s natural healing response. But does the science actually support this approach for knee arthritis ? In this post, we review the clinical trial ev
Jeffrey Peng MD
Mar 64 min read
Does Dextrose Prolotherapy Work for Rotator Cuff Pain?
By Dr. Jeffrey Peng, MD · Published March 6, 2025 · 7 min read Watch the Full Video Rotator cuff disorders are among the most common causes of shoulder pain, contributing significantly to lost function and decreased quality of life. When conservative measures such as physical therapy and activity modification fall short, many patients are offered cortisone injections. While cortisone provides strong short-term pain relief and anti-inflammatory effects, growing evidence sugge
Jeffrey Peng MD
Mar 65 min read
Prolotherapy Trigger Point Injections for Myofascial Pain: What the Research Shows
By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 5 min read Watch the Full Video Myofascial pain syndrome is one of the most common and frustrating musculoskeletal conditions encountered in clinical practice. Characterized by painful trigger points within taut bands of skeletal muscle, it can significantly diminish quality of life and prove remarkably difficult to manage. Clinicians have long relied on a multimodal approach — combining heat therapy, cardiovascular and res
Jeffrey Peng MD
Mar 55 min read
Carpal Tunnel Syndrome Injections: PRP vs Steroid vs Dextrose Prolotherapy
By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 5 min read Watch the Full Video Carpal tunnel syndrome is one of the most common causes of hand pain and numbness, affecting millions of people each year. Injections are frequently used to provide symptom relief, but which type of injection delivers the best results? A systematic review and network meta-analysis compared three injection options — platelet-rich plasma (PRP) , dextrose prolotherapy, and corticosteroids — to
Jeffrey Peng MD
Mar 54 min read
The Complete Guide to PRP Injections: Benefits, Recovery, Cost, and Evidence
By Dr. Jeffrey Peng, MD · Published March 4, 2026 · 30 min read Watch the Full Video Platelet-rich plasma (PRP) injections have generated significant attention for their ability to treat joint pain, tendon injuries, and accelerate recovery using your body’s own healing mechanisms. But with growing interest comes a flood of questions: Does PRP actually work? How does it compare to cortisone or stem cells? Is the cost justified when insurance does not cover it? In this compreh
Jeffrey Peng MD
Mar 415 min read


PRP Injection vs Physical Therapy for Tennis Elbow: What a New 2-Year Study Shows
Written by Dr. Jeffrey Peng, MD — Board-Certified Sports Medicine Physician Published: March 1, 2026 | Last Updated: March 1, 2026 Tennis elbow — medically known as lateral epicondylosis — can be one of the most frustrating conditions to deal with. It often drags on for months, sometimes even years, and many patients find that physical therapy alone does not provide lasting relief. But what if there is a treatment that goes beyond managing symptoms and actually helps repair
Jeffrey Peng MD
Mar 14 min read


Prolotherapy Trigger Point Injection for Myofascial Pain Syndrome
Myofascial pain syndrome can cause severe pain and harm people's quality of life. That’s why clinicians are always looking for new and better options to treat this debilitating condition. Prolotherapy has been around for over 70 years and has been used to treat a variety of chronic musculoskeletal conditions. So do prolotherapy trigger point injections help treat myofascial pain syndrome? Two recent clinical trials attempted to answer this question. Myofascial pain syndrome a
Jeffrey Peng MD
Aug 25, 20234 min read


Jeffrey Peng MD
Sep 30, 20220 min read


Jeffrey Peng MD
Jul 18, 20220 min read
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