By Dr. Jeffrey Peng, MD · Published March 5, 2026 · 5 min read Watch the Full Video Carpal tunnel syndrome is one of the most common causes of hand pain and numbness, affecting millions of people each year. Injections are frequently used to provide symptom relief, but which type of injection delivers the best results? A systematic review and network meta-analysis compared three injection options — platelet-rich plasma (PRP) , dextrose prolotherapy, and corticosteroids — to